PROGRAMME
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#CRISPR-Cas9 : nouvelles avancées et défis futurs
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20-22 octobre 2021 - Bordeaux, France
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Mercredi 20 octobre 2021
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14:30 - 15:00
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Reception of participants
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15:00 - 15:15
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Welcome and presentation by the organizers
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SESSION I
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Recent developments of genome editing with the CRISPR system: can it get better?
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15:15 - 16:00
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Title to be defined
Speaker to be defined
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| 16:00 - 16:30 |
Nanoblade delivery of Cas9 RNP in difficult-to-transfect cells
Emiliano Ricci (ENS Lyon, Lyon, France)
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| 16:30 - 17:00 |
High efficiency gene editing in the mouse with long single stranded DNA donors
Lydia Teboul (Hartwell, United Kingdom)
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| 17:00 - 17:30 |
Coffee Break
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| 17:30 - 18:00 |
Biasing DNA repair to increase precise gene editing
Jean-Paul Concordet (MNHN, Paris, France)
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| 18:00 - 18:45 |
Genome editing with alternative DNA damage intermediates
Alexis Komor (UCSD, San Diego, USA)
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| 18:45 - 19:30 |
Prime editing: precise and versatile genome editing without double-strand breaks or donor DNA
Andrew Anzalone (Broad Institute, Boston, USA)
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| 19:30 - 20:30 |
Round table: can it get better?
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| 20:30 |
Dinner |
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Jeudi 21 Octobre 2021
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| 06:30 - 08:30 |
Breakfast
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SESSION II
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Power and limits of CRISPR screens
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08:30 - 09:15
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Genetic screens with haploid cells
Thijn Brummelkamp (Netherlands Cancer Institute, Amsterdam)
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09:15 - 10:00
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Deeper, finer, and wider with CRISPR screens for gene function
John Doench (Broad Institute, Boston, USA)
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10:00 - 10:30
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Coffee Break
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10:30 - 11:00
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CRISPR screens to identify new regulators of viral replication
Caroline Goujon (IRIM, Montpellier, France)
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11:00 - 11:30
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In vitro and in vivo CRISPR screens
Michel Wassef (Institut Curie, Paris, France)
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SESSION III
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Novel CRISPR ways to study genome regulation and function
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11:30 - 12:00
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CRISPR-based transcriptional regulation and more
Alejandro Chavez (Columbia University, New York City, USA)
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12:00 - 12:30
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Titile to be defined
Speaker to be defined
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12:30 - 14:00
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Lunch
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14:00 - 14:45
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Title to be defined
Hans-Hermann Wessels (New York University, USA)
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14:45 - 15:15
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Transient DNA repair pathway choice
Stephan Riesenberg (Max Planck Institute, Leipzig, Germany)
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15:15 - 15:45
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Targeted diversification of gene coding sequence via dCas9 mediated base editing
Gaelen Hess (Stanford University, USA)
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15:45 - 16:20
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Coffee Break
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16:20 - 16:40
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Targeted oncogenesis with base editors
Marion Rosello (Institut Curie, Paris, France)
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16:40 - 17:00
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Poster presentation from selected abstracts
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17:00 - 19:00
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Poster Session
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19:00 - 19:30
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Discussion about the practical phase
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19:30 - 20:15
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Cocktail
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20:15
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Dinner
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Vendredi 22 octobre 2021
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| 06:30 - 08:30 |
Breakfast
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SESSION IV
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Therapeutic perspectives
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08:30 - 09:15
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CRISPR/Cas9-based therapies for beta-hemoglobinopathies
Annarita Miccio (Institut Imagine, Paris, France)
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09:15 - 10:00
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Could germline genome editing be a treatment of male infertility?
Pierre Jouannet (Paris Descartes University, Paris, France)
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10:00 - 10:30
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Coffee Break
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10:30 - 12:00
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Round table
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| 12:00 - 14:00 |
Lunch |
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| 14:00 |
Departure |
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